Structural Aspects Of Biomaterials (Spring 2007)

Video Lectures

Displaying all 25 video lectures.
Lecture 1
Course Overview
Play Video		 Course Overview
In this video lecture, Prof. Lisa Pruitt gives an overview of this course.

Topics Included: biomaterials, orthopedics, dentistry, cardiology, implants, synthetic
Lecture 2
Biocompatibility
Play Video		 Biocompatibility
In this video lecture, Prof. Lisa Pruitt introduces Biocompatibility and discusses the FDA Regulatory Agency.

Topics of this lecture: bioimplants, biocompatibility, biomaterials, FDA regulatory, bioactivity, foreign body response, inflammation, orthopedic implants, cardiovascular, dental, soft tissue, surgical, biofixation, devices, Harvey W. Wiley, adulteration, misbranding, poison squad, clinical trials, drug eluting stents
Lecture 3
Orthopedics
Play Video		 Orthopedics
(Jan 24th) In this video lecture, Prof. Lisa Pruitt lectures on Orthopedics.

Topics in this lecture: Structural aspects of bio-materials, fibrous matrix, connective tissue, collagen fibers, reticular fibers, elastic fibers, adipose (fat) connective tissue, bones, fracture, tendon, cartilage, joints, orthopedic tissues
Lecture 4
Case Study: Sulzer Recall
Play Video		 Case Study: Sulzer Recall
(Jan 26th) In this video lecture, Prof. Lisa Pruitt lectures on Sulzer Recall.

Topics in this lecture: Orthopaedics tissues, structural aspects of bio-materials, osteoarthritis, cartilage degradation, cartilage tribology: lubrification, friction and wear, arthroscopy, debridement, tissue engineering, joint replacements, Sulzer orthopedics
Lecture 5
Case Study: Hip Implant Corrosion
Play Video		 Case Study: Hip Implant Corrosion
In this video lecture, Prof. Lisa Pruitt lectures on Hip Implant Corrosion.

Topics in this lecture: Modular Hip Implant, Prosthesis, Failure analysis, SEM Analysis of Taper, Orthopedic metallic implants, crevise corrosion, corrosion basics, galvanic corrosion, pitting corrosion, intergranular corrosion, fretting
Lecture 6
Final Project Outline
Play Video		 Final Project Outline
In this video lecture, Prof. Lisa Pruitt talks about the Final Project Outline.
Lecture 7
Case Study: Sterilization
Play Video		 Case Study: Sterilization
(Feb 7th) In this video lecture, Prof. Lisa Pruitt discusses Sterilization.

Topics in this lecture: Methods of Sterilization, oxidation and aging in UHMWPE, THR with PTFE, articular surface in TJR, synthesis and structure, polyethylene, processing, ultra high molecular weigh polyethylene, glenoid retrievals, damage scoring, polymers response to radiation, oxidation, density, TEM - micro-structure evolution, Litigation
Lecture 8
Wear in Total Joint Replacements
Play Video		 Wear in Total Joint Replacements
(Feb 9th) In this video lecture, Prof. Lisa Pruitt lectures on Wear in Total Joint Replacements.

Topics in this lecture:
Litigation issues, material development, gamma radiation sterilization, Poly II (carbon fiber reinforcement), bulk crosslinking, effects of radiation on the structural and mechanical properties, WEAR in TJR, Mechanisms of Wear, RMS roughness, wear debris, fatigue wear, wear damage, wear-mediated osteolysis, Archard's law
Lecture 9
Image Not Available
Play Video		 Total Shoulder Replacements and Contact Stress
(Feb 14th) In this video lecture, Prof. Lisa Pruitt discusses Total Shoulder Replacements and Contact Stress.
Lecture 10
Contact Stress in Devices
Play Video		 Contact Stress in Devices
(Feb 16th) In this video lecture, Prof. Lisa Pruitt discusses Contact Stress in Devices and Stress Shielding.

Topics in this lecture:
Stress shielding in joint replacements, loading at hip joint, osteolysis, THR material requirements, biocompatibility, THR procedure, fixating implant, solution to fracture problem, bone loss - stress shielding, composite beam theory, compressive stress - axial loading and bending, bone resorption, conformity and contact stresses, device longevity
Lecture 11
Guest Lecture: Dr. Michael Ries
Play Video		 Guest Lecture: Dr. Michael Ries
(Feb 21st) In this video lecture, Dr. Michael Ries, Chief of Arthoroplasty, UCSF lectures for this class.

In this lecture: video showing surgery applying Cementless Press fit Acetabular cup technique, total hip replacement, polyethylene stresses
Lecture 12
UHMWPE Fatigue
Play Video		 UHMWPE Fatigue
(Feb 23rd) In this video lecture, Prof. Lisa Pruitt lectures on UHMWPE Fatigue.

In this lecture:
Failure in highly cross-linked polyethylene, micromechanisms of wear, highly cross-linked UHMWPE, mixed clinical performance, tibial insert, microscopic scanning surface damage, fatigue in TKR, processing conditions, material groups, fatigue fractography
Lecture 13
Fatigue Design
Play Video		 Fatigue Design
(Feb 28th) In this video lecture, Prof. Lisa Pruitt lectures on Fatigue Design.

Topics: Fatigue, Relevance in tissues and devices, failure modes, design philosophy, total life philosophy, stress based approach, S-N plot generation, strain based loading, cycling softening, strain based fatigue life
Lecture 14
Guest Lecture: Dr. Andy Kohm
Play Video		 Guest Lecture: Dr. Andy Kohm
(Mar 2nd) In this video lecture, Dr. Andy Kohm lectures on Spinal Implants and Kyphon.

Topics: Anatomy, spinal injury or deformity, clinical diagnosis, invertebral disc herniation, disc repair, non-repairable disc, disc replacement, fusions, spinal fusion, stabilizing implants, fusion failures, deformity correction, computer guided surgery, vertebral replacement, compression fracture, vertebroplasty, Kyphoplasty vx Vertebroplasty, burst fracture, spinal biomechanics, instant axis of rotation, functional spinal units, effect of testing parameters, spine tester, compression plate, pedicle screw system, screw orientation and fixation, biomechanical testing, cadaver testing,
Lecture 15
Defect Tolerant Philosophy
Play Video		 Defect Tolerant Philosophy
(March 7th) In this video lecture, Prof. Lisa Pruitt lectures on Defect Tolerant Philosophy.

Topics: Fracture mechanics concepts, Fatigue crack propagation, defect tolerant life prediction, toughening, choosing design philosophy
Lecture 16
Image Not Available
Play Video		 Guest Lecture: Professor Rob Ritchie
(Mar 9th) In this video lecture, Prof. Rob Ritchieear lectures on Fracture in Minerized Tissues and MSME.
Lecture 17
Dental Materials
Play Video		 Dental Materials
(March 16th) In this video lecture, Prof. Lisa Pruitt lectures on Dental Materials.

Topics:
Dental tissues and replacements, issues, the tooth, tissue constituents, enamel, dentin, structural properties, dental biomaterials, teeth replacement, amalgams and fillings, thermal expansion, implants, structural requirements, titanium implants, fatigue, design issues, temporary abutment, healing, permanent crowns, regulatory issues
Lecture 18
Guest Lecture: Vascular Mechanics
Play Video		 Guest Lecture: Vascular Mechanics
(March 21st) In this video lecture, the topic discussed is Vascular Mechanics.

Topics:
Cardiovascular system, blood vessels, aneurysm, blood pressure, elastin and collagen, vasa vasorum, arterial mechanical behavior, inflation, biaxial testing, strain energy function, residual stresses, atherosclerosis, stary's classification, finite element study, lipid pools, vulnerable plaque, dirct evaluation, treatments
Lecture 19
In Class Demonstrations: Knee, HIp, Dental, Cardio
Play Video		 In Class Demonstrations: Knee, HIp, Dental, Cardio
(Mar 23rd) In this video lecture, Prof. Lisa Pruitt discusses Knee, HIp, Dental and Cardio through some class demonstrations.
Lecture 20
Guest Lecture: Dr. Scott Robertson
Play Video		 Guest Lecture: Dr. Scott Robertson
(Apr 4th) In this video lecture, Dr. Scott Robertson lectures on Fatigue, Fracture and LBL.

Topics:
Stent Failure, failure analysis of biomedical devices, microscopy, sterilization, In Vivo failure mechanisms, explanted stent examinations, explant analysis, coronary stents, co-alloy SFA stent, crack growth mechanisms, high cycle fatigue, damage tolerance approach, flatened nitinol tube, load ratio, R-Ratio Significance, Fracture toughness, fatigue and design, overload fracture
Lecture 21
Guest Lecture: Dr. Alan Pelton
Play Video		 Guest Lecture: Dr. Alan Pelton
(April 6th) In this video lecture, Dr. Alan Pelton lectures on Stent Design and Nitinol Device Company (NDC).

Topics:
Nitinol, Austenite, martensite in 2D, lattice-invariant strain: twinning, shape memory effect, uses of nitinol, superelastic effect, stress-induced martensite, Beam Theory: strut angle, tip deflection, hoop stress, strut force, and moment. Nitinol stent cycle: crimp, RRF. Strut Length on COF. Pulsatile fatigue. Stenting diseased vessels.
Lecture 22
Soft Tissue Reconstruction
Play Video		 Soft Tissue Reconstruction
(April 18th) In this video lecture, Prof. Lisa Pruitt lectures on Soft Tissue Reconstruction.

Topics: Anatomy, vision correction, corneal implants, anatomy of the eye, structure of the cornea, corneal disorders, keratoconus, clinical treatment, device mechanisms, corneal replacement, mechanical requirements, mechanical behavior, biomaterials for corneal reconstruction, mechanical properties pf pHEMA, Poly HEMA Devices, Keratoplasty, Improving biocompatibility, Facial Implants, Rhinoplasty, European procedure, functional requirements, mechanical requirements, Failure modes, silicone rubber, Expanded poly-tetra-fluor-ethylene, Porus High Density Polyethylene, facial augmentation trends
Lecture 24
Exam Solutions
Play Video		 Exam Solutions
(Apr 25th) In this video lecture, Prof. Lisa Pruitt explains the Exam Solutions.
Lecture 26
Student Presentations I
Play Video		 Student Presentations I
(May 4th) In this video lecture, Prof. Lisa Pruitt discusses Student Presentations.

Topics:
Reducing sound in Tilting Disk Heart Valve: historical, Bjork-Shiley Convexoconcave, design specialization, device analysis. Revision TKR. Relieve pain and restore functions due to ankylosis: inflammatory arthritis, tissue graft failure, alloplastic device failure. Device replaces mandibular condyle and fossa-eminence. Hertz contact. Stress shielding analysis, fall analysis, failure analysis
Lecture 27
Student Presentations II
Play Video		 Student Presentations II
(May 9th) In this video lecture, Prof. Lisa Pruitt discusses Student Presentations once more.
Topics:
Total Knee Replacement (TKR). Fatigue Fracture of the Bolt. THR for child with osteosarcoma. Static analysis. TMJ implants: pediatrics device, design / proposal. Structure failure of pyrolytic carbon heart valves. Fracture and embolization of leaflets. Intraoperative and Postoperative failures. Cracks. Stent-graf holding valve in place. Fracture embolization of Duromedics Mitral Prosthesis: Device design, PMMA, UHMWPE. High strength TKR for professional or large athletes. Springs as schok absorbers