Useful Genetics

Video Lectures

Displaying all 98 video lectures.
I. How Different Are We?
Lecture 1
Overview of Module 1
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Overview of Module 1
Lecture 2
How different are we?
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How different are we?
Lecture 3
Properties of DNA
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Properties of DNA
Lecture 4
Properties of genes
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Properties of genes
Lecture 5
Why molecular biology is confusing
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Why molecular biology is confusing
Lecture 6
Properties of chromosomes
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Properties of chromosomes
Lecture 7
Life cycles and ploidy
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Life cycles and ploidy
Lecture 8
Comparing DNA sequences
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Comparing DNA sequences
Lecture 9
Genetic and evolutionary relationships of human populations
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Genetic and evolutionary relationships of human populations
II. Mutations
Lecture 10
Overview of Module 2
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Overview of Module 2
The overview video for Module 2 of Useful Genetics.
Lecture 11
Fidelity of DNA replication
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Fidelity of DNA replication
Lecture 12
Why most mutations are harmless
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Why most mutations are harmless
Lecture 13
Types of mutations and their consequences
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Types of mutations and their consequences
Lecture 14
Germline and Somatic Mutations
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Germline and Somatic Mutations
Lecture 15
Mutagens (what should we worry about)
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Mutagens (what should we worry about)
Lecture 16
Mutations, selection and evolvability
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Mutations, selection and evolvability
Lecture 17
Origins and evolution of new genes and gene families
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Origins and evolution of new genes and gene families
Lecture 18
Comparing DNA sequences reveals evolutionary history
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Comparing DNA sequences reveals evolutionary history
III. DNA Differences and Gene Functions
Lecture 19
Overview of Module 3
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Overview of Module 3
Lecture 20
Protein basics
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Protein basics
Lecture 21
Catalytic proteins (enzymes)
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Catalytic proteins (enzymes)
Lecture 22
Structural, transport and carrier proteins
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Structural, transport and carrier proteins
Lecture 23
Regulatory proteins and RNAs
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Regulatory proteins and RNAs
Lecture 24
Homozygous phenotypes
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Homozygous phenotypes
Lecture 25
Diploids: Heterozygous phenotypes
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Diploids: Heterozygous phenotypes
Lecture 26
All about dominance
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All about dominance
Lecture 27
How genes are named
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How genes are named
Lecture 28
Gene interaction in biochemical pathways
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Gene interaction in biochemical pathways
Lecture 29
Regulatory interactions
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Regulatory interactions
Lecture 30
How somatic mutations cause cancer
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How somatic mutations cause cancer
Lecture 31
Frameworks for predicting the phenotypic effects of mutation
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Frameworks for predicting the phenotypic effects of mutation
IV. Natural Genetic Variation
Lecture 32
Overview of Module 4
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Overview of Module 4
Lecture 33
Sex chromosomes and sex determination
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Sex chromosomes and sex determination
Lecture 34
Expression of X‐linked genes in females
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Expression of X‐linked genes in females
Lecture 35
Expression of X‐linked genes in males
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Expression of X‐linked genes in males
Lecture 36
Can natural genetic variation explain natural phenotypic variation?
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Can natural genetic variation explain natural phenotypic variation?
Lecture 37
Most natural variation has very small effects
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Most natural variation has very small effects
Lecture 38
Many natural genetic variants affect multiple traits
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Many natural genetic variants affect multiple traits
Lecture 39
Effects of natural genetic variation depend on the environment
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Effects of natural genetic variation depend on the environment
Lecture 40
Effects of natural genetic variation depend on chance
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Effects of natural genetic variation depend on chance
Lecture 41
How natural genetic variation affects the risk of cancer
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How natural genetic variation affects the risk of cancer
Lecture 42
Integrating new understanding into old concepts
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Integrating new understanding into old concepts
V. Personal Genomics
Lecture 43
Overview of Module 5
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Overview of Module 5
Lecture 44
DNA fingerprinting
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DNA fingerprinting
Lecture 45
Analyzing a single gene or gene 'panel'
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Analyzing a single gene or gene 'panel'
Lecture 46
SNP-typing the genome, Part 1
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SNP-typing the genome, Part 1
Lecture 47
SNP-typing the genome, Part 2
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SNP-typing the genome, Part 2
Lecture 48
SNP-typing services
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SNP-typing services
Lecture 49
Exome sequencing
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Exome sequencing
Lecture 50
Haplotypes
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Haplotypes
Lecture 51
Ancestry
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Ancestry
Lecture 52
Ethical and social issues surrounding personal genomics
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Ethical and social issues surrounding personal genomics
Lecture 53
Not-so-personal genomics
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Not-so-personal genomics
VI. The Mechanics of Inheritance
Lecture 54
Overview of Module 6
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Overview of Module 6
Lecture 55
Mitosis
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Mitosis
Lecture 56
Sexual life cycles
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Sexual life cycles
Lecture 57
Meiosis, the basics
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Meiosis, the basics
Lecture 58
Following genotypes through meiosis, part 1
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Following genotypes through meiosis, part 1
Lecture 59
More about meiosis: homolog pairing and crossing-over
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More about meiosis: homolog pairing and crossing-over
Lecture 60
Following genotypes through meiosis (this time with crossovers)
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Following genotypes through meiosis (this time with crossovers)
Lecture 61
Mating
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Mating
Lecture 62
Following alleles through generations
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Following alleles through generations
Lecture 63
Relatedness
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Relatedness
Lecture 64
Sex chromosomes in meiosis
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Sex chromosomes in meiosis
VII. Genetic Analysis
Lecture 65
Overview of Module 7
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Overview of Module 7
Lecture 66
Genetic analysis began with Mendel
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Genetic analysis began with Mendel
Lecture 67
Mendels findings and what we now know
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Mendels findings and what we now know
Lecture 68
How to do genetic analysis
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How to do genetic analysis
Lecture 69
Mendel's genetic analysis
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Mendel's genetic analysis
Lecture 70
Detecting sex-linkage, predicting outcomes
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Detecting sex-linkage, predicting outcomes
Lecture 71
Using crosses to investigate locations of autosomal genes
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Using crosses to investigate locations of autosomal genes
Lecture 72
Using pedigrees to investigate family inheritance
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Using pedigrees to investigate family inheritance
Lecture 73
Using crosses to investigate gene function
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Using crosses to investigate gene function
Lecture 74
Genetic analysis: numbers matter
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Genetic analysis: numbers matter
VIII. All about Breeding and Inbreeding
Lecture 75
Overview of Module 8
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Overview of Module 8
Lecture 76
Heritability
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Heritability
Lecture 77
GWAS redux
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GWAS redux
Lecture 78
Inbreeding
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Inbreeding
Lecture 79
Inbreeding in livestock and pets
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Inbreeding in livestock and pets
Lecture 80
Inbreeding and genetic variation in evolution and conservation
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Inbreeding and genetic variation in evolution and conservation
Lecture 81
Hybrids
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Hybrids
Lecture 82
Plant Breeding & Transgenics
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Plant Breeding & Transgenics
IX. Chromosomal Changes
Lecture 83
Overview of Module 9
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Overview of Module 9
Lecture 84
Polyploidy
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Polyploidy
Lecture 85
Aneuploidy
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Aneuploidy
Lecture 86
Aneuploidy for sex chromosomes
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Aneuploidy for sex chromosomes
Lecture 87
Chromosomes rearrangements
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Chromosomes rearrangements
Lecture 88
Consequences of chromosome rearrangements
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Consequences of chromosome rearrangements
Lecture 89
Small changes (structural variation)
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Small changes (structural variation)
Lecture 90
Junk and selfish DNA
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Junk and selfish DNA
Lecture 91
Genome evolution
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Genome evolution
X. Selected Advanced Topics
Lecture 92
Overview of Module 10
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Overview of Module 10
Lecture 93
Origin of Life
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Origin of Life
Lecture 94
Mitochondrial genetics
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Mitochondrial genetics
Lecture 95
Epigenetics
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Epigenetics
Lecture 96
Mosaics and chimeras
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Mosaics and chimeras
Lecture 97
Fetal DNA
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Fetal DNA
Lecture 98
Genetics of aging
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Genetics of aging