100 Greatest Discoveries (2004) Science Channel

100 Greatest Discoveries - MEDICINE

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100 Greatest Discoveries - MEDICINE

1. Human Anatomy (1538)
Andreas Vesalius dissects human corpses, revealing detailed information about human anatomy and correcting earlier views. Vesalius believes that understanding anatomy is crucial to performing surgery, so he dissects human corpses himself (unusual for the time). His anatomical charts detailing the blood and nervous systems, produced as a reference aid for his students, are copied so often that he is forced to publish them to protect their accuracy. In 1543 he publishes De Humani Corporis Fabrica, transforming the subject of anatomy.

2. Blood Circulation (1628)

William Harvey discovers that blood circulates through the body and names the heart as the organ responsible for pumping the blood. His groundbreaking work, Anatomical Essay on the Motion of the Heart and Blood in Animals, published in 1628, lays the groundwork for modern physiology.

3. Blood Groups (1902)

Austrian biologist Karl Landsteiner and his group discover four blood groups and develop a system of classification. Knowledge of the different blood types is crucial to performing safe blood transfusions, now a common practice.

4. Anesthesia (1842–1846)
Several scientists discover that certain chemicals can be used as anesthetics, making it possible to perform surgery without pain. The earliest experiments with anesthetic agents — nitrous oxide (laughing gas) and sulfuric ether — are performed mainly by 19th-century dentists.

5. X-rays (1895)
Wilhelm Roentgen accidentally discovers X-rays as he conducts experiments with the radiation from cathode rays (electrons). He notices that the rays are able to penetrate opaque black paper wrapped around a cathode ray tube, causing a nearby table to glow with florescence. His discovery revolutionizes physics and medicine, earning him the first-ever Nobel Prize for physics in 1901.

6. Germ Theory (1800s)

French chemist Louis Pasteur finds that certain microbes are disease-causing agents. At the time, the origin of diseases such as cholera, anthrax and rabies is a mystery. Pasteur formulates a germ theory, postulating that these diseases and many others are caused by bacteria. Pasteur is called the "father of bacteriology" because his work leads to a new branch of scientific study.

7. Vitamins (early 1900s)
Frederick Hopkins and others discover that some diseases are caused by deficiencies of certain nutrients, later called vitamins. Through feeding experiments with laboratory animals, Hopkins concludes that these "accessory food factors" are essential to health.

8. Penicillin (1920s–1930s)
Alexander Fleming discovers penicillin, then Howard Florey and Boris Chain isolate and purify the compound, producing the first antibiotic. Fleming's discovery comes completely by accident when he notices that mold has killed a bacteria sample in a petri dish that is languishing under a pile in his lab's sink. Fleming isolates a sample of the mold and identifies it as Penicillium notatum. With controlled experimentation, Florey and Chain later find the compound cures mice with bacterial infections.

9. Sulfa Drugs (1930s)
Gerhard Domagk discovers that Prontosil, an orange-red dye, cures infections caused by the common bacteria streptococci. The finding opens the door to the synthesis of chemotherapeutic drugs (or "wonder drugs") and sulfa drugs in particular.

10. Vaccination (1796)
Edward Jenner, an English country doctor, performs the first vaccination against smallpox after discovering that inoculation with cowpox provides immunity. Jenner formulated his theory after noticing that patients who work with cattle and had come into contact with cowpox never came down with smallpox when an epidemic ravaged the countryside in 1788.

11. Insulin (1920s)
Frederick Banting and his colleagues discover the hormone insulin, which helps balance blood sugar levels in diabetes patients and allows them to live normal lives. Before insulin, diabetes meant a slow and certain death.

12. Oncogenes (1975)
Harold Varmus and Michael Bishop discover oncogenes — normal genes that control growth in every living cell, but can contribute to converting normal cells into cancer cells if mutated or present in abnormally high amounts. Cancer cells are cells that multiply uncontrollably. Varmus and Bishop worked from the theory that the growth of cancerous cells does not occur as the result of an invasion from outside the cell, but as a result of mutations possibly aggravated by environmental toxins such as radiation or smoke.

13. The Human Retrovirus HIV (1980s)
Competing scientists Robert Gallo and Luc Montagnier separately discover a new retrovirus later dubbed HIV (human immunodeficiency virus), and identify it as the causative agent of AIDS (acquired immunodeficiency syndrome).

Documentary Description

100 GREATEST DISCOVERIES (2004)
by Discovery Channel

Scientists have transformed the way we think and live throughout the centuries. What are the most important scientific discoveries of all time? In no particular order, we present the top 100 in eight different categories:

Astronomy
Biology
Chemistry
Earth Science
Evolution
Genetics
Medicine
Physics

Bill Nye "The Science Guy" hosts a new series that highlights the greatest scientific discoveries of all time, from the earliest time to the present day. The series features nine episodes: Evolution, Earth Sciences, Medicine, Physics, Astronomy, Chemistry, Genetics and Biology, plus a wrap up episode featuring the top 10 discoveries of all time. This is a fun and instructive series, with a lot of historical re-creations, archival footage, visits to interesting scientific research facilities and interviews with present-day scientists including several Nobel laureates - all presented with the flair and humor associated with television's "Science Guy" Bill Nye.
Kathryn Coombs/ imdb.com

Product Description, by Amazon.com
Join host Bill Nye as he recounts the 100 most important discoveries and explains how each one has had a hand in shaping the modern world. Evolution & Earth Sciences: From the discovery of the dinosaur-killing KT asteroid to Carl Linnaeus' still-used life form classification system to the groundbreaking theories of Charles Darwin, learn how intelligent life began on earth. Venture beneath our planet's crust for a look at the powerful geological forces that keep life on the move and adapting  plate tectonics, earthquakes and super volcanoes. Medicine & Physics: With physician Andreas Vesalius's groundbreaking anatomical drawings in 1538, a new science was born. Witness the horror of a pre-anesthesia operating room, see how X-rays were discovered and meet the man who developed the first vitamin. Plus, learn how physicist Sir Isaac Newton developed his three laws of motion and travel inside the atom for an explosive look at Einstein's best-known theory. Astronomy & Chemistry: Copernicus first theorized that the Sun was the center of our solar system, but it took the work of Johannes Kepler to prove it. Learn why the universe is expanding and meet modern astronomers who gauge the likelihood of life "out there." Joesph Priestley initiated the study of chemistry in 1770 with the discovery of oxygen. Genetics & Biology: Gregor Mendel's work with pea plants pioneered the study of genetics, but it wasn't until the creation of the double helix DNA model that the field really began to take off. Hundreds of years before the first DNA test, "Micrographia" championed the use of microscopes and set the stage for the first major discovery in biology: microorganisms. Learn how the secret of the cell was solved and how starfish led to the development of stem cell research. Top Ten Discoveries: What are the 10 greatest scientific discoveries of all time? Find out which of the original 100 were voted by viewers as the most groundbreaking.

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