Recorded on April 24, 2012

Index of Topics:

1:19-Electrophilicity of Aldehydes and Ketones
5:37-Hydrates
12:17-Acid-Catalyzed Addition of Water to Acetone
21:29-Acetone Enol Example
24:01-Reverse Reaction
25:31-Energy Diagram
29:28-Reverse Reaction Mechanism
36:38-Acid-Catalyzed Acetal Formation
40:00-Hemiacetal
43:01-Strong Acid
47:23-Hemiacetal Formation Mechanism
50:52-Hemiacetal to Acetal Mechanism
1:00:52-Acid-Catalyzed Acetal Hydrolysis
1:06:12-Protecting Groups
1:12:15-Cyclic Hemiacetal

1. Introduction to Carboxylic Acids.
2. Reactivity of Carbonyl Compounds.
3. Reactions of Organometallic Reagents.
4. Reactions and Protecting Groups.
5. Aldehydes and Ketones: Reactions.
6. Formation of Imines & Enamines from Aldehydes & Ketones.
7. Acid-Catalyzed Formation of Hydrates, Hemiacetals, & Acetals.
8. The Chemistry of the Carboxylic Acid Family.
9. Reactions of Carboxylic Acids, Esters, Amides, & Nitriles.
10. Enols and Enolates.
11. More Reactions of Enols and Enolates.
12. The Aldol Reaction and the Michael Reaction.
13. The Robinson Annulation and the Claisen Reaction.
14. Introduction to Amines: Properties and Synthesis.
15. Hofmann Degradation, Diazotization, & Aryl Diazonium Salts.
16. Introduction to Carbohydrates: Structure and Stereochemistry
17. More Structure, Stereochemistry, & Reactions of Carbohydrates.
18. Amino Acids, Peptides, and Proteins.
19. Organometallic Reactions in Organic Synthesis.

This is the third quarter course in the organic chemistry series. Topics covered include: Fundamental concepts relating to carbon compounds with emphasis on structural theory and the nature of chemical bonding, stereochemistry, reaction mechanisms, and spectroscopic, physical, and chemical properties of the principal classes of carbon compounds.

Organic Chemistry 51C is part of OpenChem. http://ocw.uci.edu/collections/open_chem