Recorded on May 15, 2012

Index of Topics:

1:28-Enolate Formation
3:56-Aldol Reaction
11:44-Retrosynthesis Example
18:40-Original Aldol
21:32-Aldol Mechanism
26:45-Features of Aldol Mechanism
35:25-Aldol Example
38:21-Synthesis Example
43:16-Stereochemistry
46:46-Crossed Aldol Reaction
52:48-Intramolecular Aldol Reaction
1:01:10-Retrosynthesis of Intramolecular Aldol Reaction
1:03:16-The Michael Reaction
1:05:34-Resonance Structures
1:08:27-Strongly Basic Nucleophiles
1:12:52-Michael Reaction Mechanism
1:16:35-Retrosynthesis Example

1. Introduction to Carboxylic Acids.
2. Reactivity of Carbonyl Compounds.
3. Reactions of Organometallic Reagents.
4. Reactions and Protecting Groups.
5. Aldehydes and Ketones: Reactions.
6. Formation of Imines & Enamines from Aldehydes & Ketones.
7. Acid-Catalyzed Formation of Hydrates, Hemiacetals, & Acetals.
8. The Chemistry of the Carboxylic Acid Family.
9. Reactions of Carboxylic Acids, Esters, Amides, & Nitriles.
10. Enols and Enolates.
11. More Reactions of Enols and Enolates.
12. The Aldol Reaction and the Michael Reaction.
13. The Robinson Annulation and the Claisen Reaction.
14. Introduction to Amines: Properties and Synthesis.
15. Hofmann Degradation, Diazotization, & Aryl Diazonium Salts.
16. Introduction to Carbohydrates: Structure and Stereochemistry
17. More Structure, Stereochemistry, & Reactions of Carbohydrates.
18. Amino Acids, Peptides, and Proteins.
19. Organometallic Reactions in Organic Synthesis.

This is the third quarter course in the organic chemistry series. Topics covered include: Fundamental concepts relating to carbon compounds with emphasis on structural theory and the nature of chemical bonding, stereochemistry, reaction mechanisms, and spectroscopic, physical, and chemical properties of the principal classes of carbon compounds.

Organic Chemistry 51C is part of OpenChem. http://ocw.uci.edu/collections/open_chem