(Feb 7th) In this video lecture, Prof. Lisa Pruitt discusses Sterilization.

Topics in this lecture: Methods of Sterilization, oxidation and aging in UHMWPE, THR with PTFE, articular surface in TJR, synthesis and structure, polyethylene, processing, ultra high molecular weigh polyethylene, glenoid retrievals, damage scoring, polymers response to radiation, oxidation, density, TEM - micro-structure evolution, Litigation

1. Course Overview
2. Biocompatibility
3. Orthopedics
4. Case Study: Sulzer Recall
5. Case Study: Hip Implant Corrosion
6. Final Project Outline
7. Case Study: Sterilization
8. Wear in Total Joint Replacements
9. Total Shoulder Replacements and Contact Stress
10. Contact Stress in Devices
11. Guest Lecture: Dr. Michael Ries
12. UHMWPE Fatigue
13. Fatigue Design
14. Guest Lecture: Dr. Andy Kohm
15. Defect Tolerant Philosophy
16. Guest Lecture: Professor Rob Ritchie
17. Dental Materials
18. Guest Lecture: Vascular Mechanics
19. In Class Demonstrations: Knee, HIp, Dental, Cardio
20. Guest Lecture: Dr. Scott Robertson
21. Guest Lecture: Dr. Alan Pelton
22. Soft Tissue Reconstruction
23. Exam Solutions
24. Student Presentations I
25. Student Presentations II

This course of UC Berkeley - Bio Engineering/ME C117: Structural Aspects of Biomaterials - provides an overview of medical devices, FDA regulatory issues, biocompatibility and sterilization technology. It examines biomechanical properties: isotropy/anisotropy, stiffness, bending stresses, contact stresses, multiaxial loading, plasticity, fatigue, fracture, wear, corrosion, design issues. Also covered: Orthopedics, Dental, Cardiovascular, and Soft Tissue Reconstruction.Professor Pruitt's current research is focused on fatigue and fracture micromechanisms, cyclic damage zones, and evolution of structure due to cyclic loading and environment in advanced polymers and biomaterials.