Recorded on April 26, 2012

Index of Topics:

2:00-Carboxylic Acid Derivatives
5:54-Nomenclature
17:44-Acid Chlorides and Anhydrides
22:28-Boiling Points of Esters Versus Alkanes
26:22-Resonance Structures
28:59-Properties of Amides
35:12-IR Spectroscopy
43:51-Reaction of Acid Chloride and Anhydride in Water
45:05-Reaction of Esters and Amides in Water
51:58-NMR of Carbonyls
54:51-Carboxylic Acid Derivatives and Nucleophiles
58:08-Weakly Basic Nucleophiles
1:00:49-Balanced Equation Example
1:05:19-Student Question
1:09:28-Acid Chloride Reaction Example
1:14:11-Relative Reactivity of Carboxylic Acid Derivatives
1:17:44-Anhydride Reaction

1. Introduction to Carboxylic Acids.
2. Reactivity of Carbonyl Compounds.
3. Reactions of Organometallic Reagents.
4. Reactions and Protecting Groups.
5. Aldehydes and Ketones: Reactions.
6. Formation of Imines & Enamines from Aldehydes & Ketones.
7. Acid-Catalyzed Formation of Hydrates, Hemiacetals, & Acetals.
8. The Chemistry of the Carboxylic Acid Family.
9. Reactions of Carboxylic Acids, Esters, Amides, & Nitriles.
10. Enols and Enolates.
11. More Reactions of Enols and Enolates.
12. The Aldol Reaction and the Michael Reaction.
13. The Robinson Annulation and the Claisen Reaction.
14. Introduction to Amines: Properties and Synthesis.
15. Hofmann Degradation, Diazotization, & Aryl Diazonium Salts.
16. Introduction to Carbohydrates: Structure and Stereochemistry
17. More Structure, Stereochemistry, & Reactions of Carbohydrates.
18. Amino Acids, Peptides, and Proteins.
19. Organometallic Reactions in Organic Synthesis.

This is the third quarter course in the organic chemistry series. Topics covered include: Fundamental concepts relating to carbon compounds with emphasis on structural theory and the nature of chemical bonding, stereochemistry, reaction mechanisms, and spectroscopic, physical, and chemical properties of the principal classes of carbon compounds.

Organic Chemistry 51C is part of OpenChem. http://ocw.uci.edu/collections/open_chem