Recorded on May 3, 2012

Index of Topics:

1:16-Reactivity of Ketones
3:02-Enols
6:36-Enolate Anion
9:47-Enolates and Electrophiles
16:49-Equilibrium Between Tautomers
23:07-Acid-Catalyzed Enol Formation
29:18-Energy Diagram
37:51-Multiple Additions
46:41-pKa of Alpha Protons
53:05-Base-Catalyzed Enol Formation
58:56-Stereochemistry
1:03:42-LDA
1:11:28-Kinetic Product vs Thermodynamic Product
1:17:56-LDA and Stereochemistry

1. Introduction to Carboxylic Acids.
2. Reactivity of Carbonyl Compounds.
3. Reactions of Organometallic Reagents.
4. Reactions and Protecting Groups.
5. Aldehydes and Ketones: Reactions.
6. Formation of Imines & Enamines from Aldehydes & Ketones.
7. Acid-Catalyzed Formation of Hydrates, Hemiacetals, & Acetals.
8. The Chemistry of the Carboxylic Acid Family.
9. Reactions of Carboxylic Acids, Esters, Amides, & Nitriles.
10. Enols and Enolates.
11. More Reactions of Enols and Enolates.
12. The Aldol Reaction and the Michael Reaction.
13. The Robinson Annulation and the Claisen Reaction.
14. Introduction to Amines: Properties and Synthesis.
15. Hofmann Degradation, Diazotization, & Aryl Diazonium Salts.
16. Introduction to Carbohydrates: Structure and Stereochemistry
17. More Structure, Stereochemistry, & Reactions of Carbohydrates.
18. Amino Acids, Peptides, and Proteins.
19. Organometallic Reactions in Organic Synthesis.

This is the third quarter course in the organic chemistry series. Topics covered include: Fundamental concepts relating to carbon compounds with emphasis on structural theory and the nature of chemical bonding, stereochemistry, reaction mechanisms, and spectroscopic, physical, and chemical properties of the principal classes of carbon compounds.

Organic Chemistry 51C is part of OpenChem. http://ocw.uci.edu/collections/open_chem