Copyright Information: Penner, Reginald Thermodynamics and Chemical Dynamics 131C (UCI OpenCourseWare: University of California, Irvine), http://ocw.uci.edu/courses/chem_131c_thermodynamics_and_chem... [January 28, 2015]. License: Creative Commons Attribution-ShareAlike 3.0 United States License. (http://creativecommons.org/licenses/by-sa/3.0/us/deed.en_US).
Slide Information 00:06- Enzymes 00:14- Midterm II Results 01:12- How Am I Doing? 06:36- Today: Lindemann-Hinshelwood Mechanism, Enzyme Kinetics 07:58- Most Elementary Reactions are Either Unimolecular or Biomolecular 09:45- The Lindmann-Hinshelwood Mechanism Provides an Explanation 11:22- Can We Apply the Steady-State Approximation to this Mechanism? 12:52- What Does it Predict? 14:28- What Does This Mean Mechanistically? 16:20- Let's Apply the Steady-State Approximation 16:53- The Kinetics of Pressure-Dependent Reactions 20:08- If the LH Mechanism is Operating...Plot 20:45- Plot: Does it Work? 21:16- LH Mechanism: A Mechanism for Which a Pre-Equilibrium is Established 22:03- The Reaction Will Have an Apparent Second Order 22:34- Apply Mathematics to the Enzyme 24:42- Schematic Illustration of Enzyme Kinetics 26:35- Kinetic Scheme/Steady State Approximation Applied 28:52- Solving for [(ES)] 30:05- Obtaining the Michaelis -Menten Equation
In Chemistry 131C, students will study how to calculate macroscopic chemical properties of systems. This course will build on the microscopic understanding (Chemical Physics) to reinforce and expand your understanding of the basic thermo-chemistry concepts from General Chemistry (Physical Chemistry.) We then go on to study how chemical reaction rates are measured and calculated from molecular properties. Topics covered include: Energy, entropy, and the thermodynamic potentials; Chemical equilibrium; and Chemical kinetics.
Chemistry Dept. | Physical Sciences Sch. | University of California, Irvine