Recorded on April 12, 2012

Index of Topics:
-1:36 Ketone/Aldehyde Reduction
-5:56 Grignard Reagents
-12:31 Polarity of Grignard Reagent
-16:01 Basicity of Grignard Reagent
-19:22 Grignard Reagents and Water/Alcohol
-21:32 Organolithium Reagent
-25:50 Acetylide Anions
-34:07 Making Acetylide Anion
-38:29 Reactivity of the Carboxylic Acid Family
-44:56 Addition-Elimination Reaction
-48:12 Examples of Carboxylic Acid Reduction
-53:29 Multiple Additions onto Carboxylic Acids
-59:50 Leaving Groups
-1:08:27 Synthesizing Example
-1:16:54 More Examples of Synthesizing

1. Introduction to Carboxylic Acids.
2. Reactivity of Carbonyl Compounds.
3. Reactions of Organometallic Reagents.
4. Reactions and Protecting Groups.
5. Aldehydes and Ketones: Reactions.
6. Formation of Imines & Enamines from Aldehydes & Ketones.
7. Acid-Catalyzed Formation of Hydrates, Hemiacetals, & Acetals.
8. The Chemistry of the Carboxylic Acid Family.
9. Reactions of Carboxylic Acids, Esters, Amides, & Nitriles.
10. Enols and Enolates.
11. More Reactions of Enols and Enolates.
12. The Aldol Reaction and the Michael Reaction.
13. The Robinson Annulation and the Claisen Reaction.
14. Introduction to Amines: Properties and Synthesis.
15. Hofmann Degradation, Diazotization, & Aryl Diazonium Salts.
16. Introduction to Carbohydrates: Structure and Stereochemistry
17. More Structure, Stereochemistry, & Reactions of Carbohydrates.
18. Amino Acids, Peptides, and Proteins.
19. Organometallic Reactions in Organic Synthesis.

This is the third quarter course in the organic chemistry series. Topics covered include: Fundamental concepts relating to carbon compounds with emphasis on structural theory and the nature of chemical bonding, stereochemistry, reaction mechanisms, and spectroscopic, physical, and chemical properties of the principal classes of carbon compounds.

Organic Chemistry 51C is part of OpenChem. http://ocw.uci.edu/collections/open_chem