The Global Polio Eradication Initiative, the largest public health campaign ever launched, began in 1988 with the ambition of achieving its goal by the year 2000. In the decade since this deadline was missed, the initiative has suffered a number of setbacks, notably in the tropical world. Four major types of problems have impeded the eradication effort: operational, biological, political and religious. Northern Nigeria offers a case study of all of these factors, with domestic political and religious conflict, unsanitary conditions, and suspicion of Western medicine all undermining the anti-polio campaign. One of the questions raised by the campaign's struggle is whether or not eradication is itself a realistic public health goal, and to what extent smallpox furnishes a model precedent or a potentially misleading dream scenario.

Reading assignment:
Snowden, "Emerging and Re-emerging Diseases: A Historical Perspective"

1. Introduction to the Course
2. Classical Views of Disease: Hippocrates, Galen, and Humoralism
3. Plague (I): Pestilence as Disease
4. Plague (II): Responses and Measures
5. Plague (III): Illustrations and Conclusions
6. Smallpox (I): 'The Speckled Monster'
7. Smallpox (II): Jenner, Vaccination, and Eradication
8. Nineteenth-Century Medicine: The Paris School of Medicine
9. Asiatic Cholera (I): Personal Reflections
10. Asiatic Cholera (II): Five Pandemics
11. The Sanitary Movement and the 'Filth Theory of Disease'
12. Syphilis: From the "Great Pox" to the Modern Version
13. Contagionism versus Anticontagionsim
14. The Germ Theory of Disease
15. Tropical Medicine as a Discipline
16. Malaria (I): The Case of Italy
17. Malaria (II): The Global Challenge
18. Tuberculosis (I): The Era of Consumption
19. Tuberculosis (II): After Robert Koch
20. Pandemic Influenza
21. The Tuskegee Experiment
22. AIDS (I)
23. AIDS (II)
24. Poliomyelitis: Problems of Eradication
25. SARS, Avian Inluenza, and Swine Flu: Lessons and Prospects
26. Final Q&A

This course consists of an international analysis of the impact of epidemic diseases on western society and culture from the bubonic plague to HIV/AIDS and the recent experience of SARS and swine flu. Leading themes include: infectious disease and its impact on society; the development of public health measures; the role of medical ethics; the genre of plague literature; the social reactions of mass hysteria and violence; the rise of the germ theory of disease; the development of tropical medicine; a comparison of the social, cultural, and historical impact of major infectious diseases; and the issue of emerging and re-emerging diseases.

Course Structure:
This Yale College course, taught on campus twice per week for 50 minutes, was recorded for Open Yale Courses in Spring 2010.